Semalgid 4 mg
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PACK: 4mg / 3ml
Active substance: Semaglutide
Semaglutide: Overview and Benefits
Semaglutide is a medication primarily used to treat type 2 diabetes, and it has only recently been used for weight management. Semaglutide is a type of medication known as GLP-1 receptor agonists, and the drug class initiates insulin secretion, inhibits glucagon secretion, and slows gastric emptying through an imitation of the action of the hormone GLP-1 (glucagon-like peptide-1).
Mechanism of Effect
Semaglutide triggers GLP-1 receptors in the pancreas to discharge additional insulin following meals and to suppress the release of glucagon, a hormone that elevates blood glucose levels. This double-barreled activity controls blood glucose levels more effectively. It also increases satiety through the slowing of stomach emptying, and this may lead to weight loss.
Usage areas
1. Type 2 Diabetes: Semaglutide is indicated to enhance glycemic control in adults with type 2 diabetes mellitus. It may be used as monotherapy or with other antidiabetic drugs.
2. Weight Control: More recently, semaglutide has also been approved to control chronic weight in obese patients or with at least one condition that is weight-associated (e.g., high blood pressure, type 2 diabetes, or high cholesterol). Clinical trials showed that the participants who took semaglutide lost significant weight relative to the participants who took a placebo.
Dosage and Application
Semaglutide can either be injected or taken orally. It is often taken weekly in the form of an injection, and daily as an oral ingestion. The amount would vary according to the disease that it will be used for, as well as in conjunction with how receptive the patient would be to taking the drug.
Clinical Efficacy
Evidence has confirmed that semaglutide is effective in lowering HbA1c and weight loss. For example, the SUSTAIN and STEP clinical trial programs showed that semaglutide lowered HbA1c and body weight compared with placebo and other background therapy.
Side effects
Side effects of semaglutide are nausea, vomiting, diarrhea and constipation. The side effects are moderate to mild and also fade away in a period of time as the body gets adjusted to the medicine. There are also severe side effects such as pancreatitis or kidney damage and the patient has to visit regularly.
Conclusion
Semaglutide is a major innovation in the management of type 2 diabetes and obesity. Its potential to enhance blood glucose control and induce notable weight loss makes it an attractive choice for the majority of patients. Like any medication, semaglutide should be used with caution under the supervision of a healthcare provider to maximize its effectiveness and safety.Sources
For additional details, you can search your health care professionals or visit [FDA's medication guide](https://www.fda.gov/) and [clinical trial data](https://www.clinicaltrials.gov/)
